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Accelerated development of instability-induced osteoarthritis in transgenic mice overexpressing SOST

Objective: Sclerostin (SOST), acting as a Wnt antagonist, has been shown to play a key role in regulating bone homestasis, and has also been linked to osteoarthritis (OA) development. Here, we investigated whether overexpressing SOST could affect OA development after destabilization of the medial me...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Zhou, Sheng, Ge, Yuxiang, Li, Yixuan, Bao, Zhengyuan, Yao, Chen, Teng, Huajian, Jiang, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965855/
https://ncbi.nlm.nih.gov/pubmed/31966426
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