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Histone deacetylase 4 alters cartilage homeostasis in human osteoarthritis

BACKGROUND: Osteoarthritis (OA) is the most common degenerative joint disorder, and a major cause of pain and disability among the elderly. Histone deacetylase 4 (HDAC4) has been shown to be a key regulator of chondrocyte hypertrophy during skeletogenesis. The aims of present study were to investiga...

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Detalhes bibliográficos
Publicado no:BMC Musculoskelet Disord
Main Authors: Lu, Jingwei, Sun, Ye, Ge, Qiting, Teng, Huajian, Jiang, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300609/
https://ncbi.nlm.nih.gov/pubmed/25515592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-15-438
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