Histone deacetylase 4 alters cartilage homeostasis in human osteoarthritis

BACKGROUND: Osteoarthritis (OA) is the most common degenerative joint disorder, and a major cause of pain and disability among the elderly. Histone deacetylase 4 (HDAC4) has been shown to be a key regulator of chondrocyte hypertrophy during skeletogenesis. The aims of present study were to investiga...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Musculoskelet Disord
Auteurs principaux: Lu, Jingwei, Sun, Ye, Ge, Qiting, Teng, Huajian, Jiang, Qing
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300609/
https://ncbi.nlm.nih.gov/pubmed/25515592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-15-438
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