Praziquantel ameliorates CCl(4)‐induced liver fibrosis in mice by inhibiting TGF‐β/Smad signalling via up‐regulating Smad7 in hepatic stellate cells

BACKGROUND AND PURPOSE: Praziquantel is a schistosomicide, which has been used for more than 30 years due to its efficiency, safety, and mild side effects. Previous studies showed that prolonged treatment with praziquantel suppressed the development of liver fibrosis in mice with schistosomiasis. In...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Br J Pharmacol
Hlavní autoři: Liu, Jinfeng, Kong, Delong, Qiu, Jingfan, Xie, Yanci, Lu, Zhongkui, Zhou, Chunlei, Liu, Xinjian, Zhang, Rong, Wang, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965681/
https://ncbi.nlm.nih.gov/pubmed/31412137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14831
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky