Praziquantel ameliorates CCl(4)‐induced liver fibrosis in mice by inhibiting TGF‐β/Smad signalling via up‐regulating Smad7 in hepatic stellate cells

BACKGROUND AND PURPOSE: Praziquantel is a schistosomicide, which has been used for more than 30 years due to its efficiency, safety, and mild side effects. Previous studies showed that prolonged treatment with praziquantel suppressed the development of liver fibrosis in mice with schistosomiasis. In...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Liu, Jinfeng, Kong, Delong, Qiu, Jingfan, Xie, Yanci, Lu, Zhongkui, Zhou, Chunlei, Liu, Xinjian, Zhang, Rong, Wang, Yong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965681/
https://ncbi.nlm.nih.gov/pubmed/31412137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14831
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