Praziquantel Targets M1 Macrophages and Ameliorates Splenomegaly in Chronic Schistosomiasis

Splenomegaly is a common feature of many infectious diseases, including schistosomiasis japonica. However, the immunopathogenesis and the treatment of splenomegaly due to schistosomiasis have been largely neglected. Praziquantel (PZQ), a classical schistosomicide, has been demonstrated by us and oth...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Kong, Delong, Zhou, Chunlei, Guo, Hongfei, Wang, Wei, Qiu, Jingfan, Liu, Xinjian, Liu, Jinfeng, Wang, Lijuan, Wang, Yong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740360/
https://ncbi.nlm.nih.gov/pubmed/29061758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00005-17
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