Promethazine Exhibits Antiparasitic Properties In Vitro and Reduces Worm Burden, Egg Production, Hepatomegaly, and Splenomegaly in a Schistosomiasis Animal Model

The treatment and control of schistosomiasis, a neglected disease that affects more than 200 million people worldwide, rely on the use of a single drug, praziquantel. A vaccine has yet to be developed, and since new drug design and development is a lengthy and costly process, drug repurposing is a p...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Roquini, Daniel B., Cogo, Ramon M., Mengarda, Ana C., Mazloum, Susana F., Morais, Cristiane S., Xavier, Rogério P., Salvadori, Maria C., Teixeira, Fernanda S., Ferreira, Luiz E., Pinto, Pedro L., Morais, Thiago R., de Moraes, Josué
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879219/
https://ncbi.nlm.nih.gov/pubmed/31527034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01208-19
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