Promethazine Exhibits Antiparasitic Properties In Vitro and Reduces Worm Burden, Egg Production, Hepatomegaly, and Splenomegaly in a Schistosomiasis Animal Model

The treatment and control of schistosomiasis, a neglected disease that affects more than 200 million people worldwide, rely on the use of a single drug, praziquantel. A vaccine has yet to be developed, and since new drug design and development is a lengthy and costly process, drug repurposing is a p...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Roquini, Daniel B., Cogo, Ramon M., Mengarda, Ana C., Mazloum, Susana F., Morais, Cristiane S., Xavier, Rogério P., Salvadori, Maria C., Teixeira, Fernanda S., Ferreira, Luiz E., Pinto, Pedro L., Morais, Thiago R., de Moraes, Josué
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879219/
https://ncbi.nlm.nih.gov/pubmed/31527034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01208-19
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