Paclitaxel ameliorates fibrosis in hepatic stellate cells via inhibition of TGF-β/Smad activity

AIM: To investigated if paclitaxel can attenuate hepatic fibrosis in rat hepatic stellate cells (RHSCs). METHODS: RHSCs were cultured in vitro and randomly assigned to four groups: normal control group (treated only with Dulbecco’s Modified Eagle’s Medium), Taxol group (200 nmol/L paclitaxel was add...

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Autors principals: Zhou, Jun, Zhong, De-Wu, Wang, Qun-Wei, Miao, Xiong-Ying, Xu, Xun-Di
Format: Artigo
Idioma:Inglês
Publicat: Baishideng 2010
Matèries:
Brief Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900727/
https://ncbi.nlm.nih.gov/pubmed/20614491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i26.3330
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