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Magnesium Isoglycyrrhizinate Ameliorates Fibrosis and Disrupts TGF-β-Mediated SMAD Pathway in Activated Hepatic Stellate Cell Line LX2

Liver fibrosis is a histological change often attributed to the activation of hepatic stellate cells (HSCs) and the excessive formation of scar tissues in the liver. Advanced stages of the disease frequently lead to cirrhosis. Magnesium isoglycyrrhizinate (MgIG) has been accepted as a hepatoprotecti...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Tee, Jie Kai, Peng, Fei, Tan, Yeong Lan, Yu, Bo, Ho, Han Kiat
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167412/
https://ncbi.nlm.nih.gov/pubmed/30319402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01018
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