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Immune Response Mechanisms against AAV Vectors in Animal Models
Early preclinical studies in rodents and other species did not reveal that vector or transgene immunity would present a significant hurdle for sustained gene expression. While there was early evidence of mild immune responses to adeno-associated virus (AAV) in preclinical studies, it was generally b...
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| Опубликовано в: : | Mol Ther Methods Clin Dev |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Gene & Cell Therapy
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6965504/ https://ncbi.nlm.nih.gov/pubmed/31970198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.12.008 |
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