Improvement of epidermal covering on AEC patients with severe skin erosions by PRIMA-1(MET)/APR-246

P63 is a major transcription factor regulating skin development and homeostasis. It controls many genes involved in cell proliferation, adhesion, and early differentiation. P63 is mutated in several rare syndromes called p63-related ectodermal dysplasia syndromes (ED). The main forms are EEC and AEC...

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Vydáno v:Cell Death Dis
Hlavní autoři: Aberdam, Edith, Roux, Lauriane N., Secrétan, Philippe-Henri, Boralevi, Franck, Schlatter, Joël, Morice-Picard, Fanny, Sol, Stefano, Bodemer, Christine, Missero, Caterina, Cisternino, Salvatore, Aberdam, Daniel, Hadj-Rabia, Smail
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965199/
https://ncbi.nlm.nih.gov/pubmed/31949132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2223-8
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