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Infertility Caused by Inefficient Apoptotic Germ Cell Clearance in Xkr8-Deficient Male Mice

During spermatogenesis, up to 75% of germ cells in the testes undergo apoptosis and are cleared by Sertoli cells. X-linked XK blood group-related 8 (Xkr8) is a plasma membrane protein that scrambles phospholipids in response to apoptotic signals, exposing phosphatidylserine (PtdSer). Here, we found...

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Publicat a:Mol Cell Biol
Autors principals: Yamashita, Yahiro, Suzuki, Chigure, Uchiyama, Yasuo, Nagata, Shigekazu
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965033/
https://ncbi.nlm.nih.gov/pubmed/31712393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00402-19
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