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Phosphorylation-mediated activation of mouse Xkr8 scramblase for phosphatidylserine exposure

The exposure of phosphatidylserine (PtdSer) to the cell surface is regulated by the down-regulation of flippases and the activation of scramblases. Xkr8 has been identified as a scramblase that is activated during apoptosis, but its exogenous expression in the mouse Ba/F3 pro B cell line induces con...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Sakuragi, Takaharu, Kosako, Hidetaka, Nagata, Shigekazu
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386700/
https://ncbi.nlm.nih.gov/pubmed/30718401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820499116
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