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TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets

Phosphatidylserine (PtdSer) exposure on the surface of activated platelets requires the action of a phospholipid scramblase(s), and serves as a scaffold for the assembly of the tenase and prothrombinase complexes involved in blood coagulation. Here, we found that the activation of mouse platelets wi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fujii, Toshihiro, Sakata, Asuka, Nishimura, Satoshi, Eto, Koji, Nagata, Shigekazu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611630/
https://ncbi.nlm.nih.gov/pubmed/26417084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516594112
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