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Characterization of the scrambling domain of the TMEM16 family

The TMEM16 protein family has 10 members, each of which carries 10 transmembrane segments. TMEM16A and 16B are Ca(2+)-activated Cl(−) channels. Several other members, including TMEM16F, promote phospholipid scrambling between the inner and outer leaflets of a cell membrane in response to intracellul...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Gyobu, Sayuri, Ishihara, Kenji, Suzuki, Jun, Segawa, Katsumori, Nagata, Shigekazu
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474828/
https://ncbi.nlm.nih.gov/pubmed/28559311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703391114
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