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Phospholipid flippases enable precursor B cells to flee engulfment by macrophages

ATP11A and ATP11C, members of the P4-ATPases, are flippases that translocate phosphatidylserine (PtdSer) from the outer to inner leaflet of the plasma membrane. Using the W3 T lymphoma cell line, we found that Ca(2+) ionophore-induced phospholipid scrambling caused prolonged PtdSer exposure in cells...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Segawa, Katsumori, Yanagihashi, Yuichi, Yamada, Kyoko, Suzuki, Chigure, Uchiyama, Yasuo, Nagata, Shigekazu
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275493/
https://ncbi.nlm.nih.gov/pubmed/30355768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814323115
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