טוען...
Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner
Extrachromosomal DNA can integrate into the genome with no sequence specificity producing an insertional mutation. This process, which is referred to as random integration (RI), requires a double stranded break (DSB) in the genome. Inducing DSBs by various means, including ionizing radiation, increa...
שמור ב:
| הוצא לאור ב: | PLoS Genet |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6964834/ https://ncbi.nlm.nih.gov/pubmed/31945059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008550 |
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