Evaluation of the Spatial Distribution of γH2AX following Ionizing Radiation

An early molecular response to DNA double-strand breaks (DSBs) is phosphorylation of the Ser-139 residue within the terminal SQEY motif of the histone H2AX(1,2). This phosphorylation of H2AX is mediated by the phosphatidyl-inosito 3-kinase (PI3K) family of proteins, ataxia telangiectasia mutated (AT...

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Autores principales: Vasireddy, Raja S., Tang, Michelle M., Mah, Li-Jeen, Georgiadis, George T., El-Osta, Assam, Karagiannis, Tom C.
Formato: Artigo
Lenguaje:Inglês
Publicado: MyJove Corporation 2010
Materias:
Cellular Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156025/
https://ncbi.nlm.nih.gov/pubmed/20736911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2203
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