Evaluation of the efficacy of radiation-modifying compounds using γH2AX as a molecular marker of DNA double-strand breaks

Radiation therapy is a widely used therapeutic approach for cancer. To improve the efficacy of radiotherapy there is an intense interest in combining this modality with two broad classes of compounds, radiosensitizers and radioprotectors. These either enhance tumour-killing efficacy or mitigate dama...

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Bibliografiska uppgifter
Huvudupphovsmän: Mah, Li-Jeen, Orlowski, Christian, Ververis, Katherine, Vasireddy, Raja S, El-Osta, Assam, Karagiannis, Tom C
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037297/
https://ncbi.nlm.nih.gov/pubmed/21261999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-2-3
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