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Calibration of the γ-H2AX DNA Double Strand Break Focus Assay for Internal Radiation Exposure of Blood Lymphocytes

DNA double strand break (DSB) formation induced by ionizing radiation exposure is indicated by the DSB biomarkers γ-H2AX and 53BP1. Knowledge about DSB foci formation in-vitro after internal irradiation of whole blood samples with radionuclides in solution will help us to gain detailed insights abou...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Eberlein, Uta, Peper, Michel, Fernández, Maria, Lassmann, Michael, Scherthan, Harry
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390303/
https://ncbi.nlm.nih.gov/pubmed/25853575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123174
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