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Pathway choice in DNA double strand break repair: observations of a balancing act
Proper repair of DNA double strand breaks (DSBs) is vital for the preservation of genomic integrity. There are two main pathways that repair DSBs, Homologous recombination (HR) and Non-homologous end-joining (NHEJ). HR is restricted to the S and G2 phases of the cell cycle due to the requirement for...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3557175/ https://ncbi.nlm.nih.gov/pubmed/23181949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-3-9 |
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