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LIN28B Impairs the Transition of hESC-Derived β Cells from the Juvenile to Adult State

Differentiation of human embryonic stem cells into pancreatic β cells holds great promise for the treatment of diabetes. Recent advances have led to the production of glucose-responsive insulin-secreting cells in vitro, but resulting cells remain less mature than their adult primary β cell counterpa...

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Dades bibliogràfiques
Publicat a:Stem Cell Reports
Autors principals: Zhou, Xin, Nair, Gopika G., Russ, Holger A., Belair, Cassandra D., Li, Mei-Lan, Shveygert, Mayya, Hebrok, Matthias, Blelloch, Robert
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962644/
https://ncbi.nlm.nih.gov/pubmed/31883920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.11.009
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