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LIN28B Impairs the Transition of hESC-Derived β Cells from the Juvenile to Adult State
Differentiation of human embryonic stem cells into pancreatic β cells holds great promise for the treatment of diabetes. Recent advances have led to the production of glucose-responsive insulin-secreting cells in vitro, but resulting cells remain less mature than their adult primary β cell counterpa...
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| Pubblicato in: | Stem Cell Reports |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6962644/ https://ncbi.nlm.nih.gov/pubmed/31883920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.11.009 |
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