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Extracellular pH and intracellular phosphatidylinositol 4,5-bisphosphate control Cl(−) currents in guinea pig detrusor smooth muscle cells

Cl(−) channels serve as key regulators of excitability and contractility in vascular, intestinal, and airway smooth muscle cells. We recently reported a Cl(−) conductance in detrusor smooth muscle (DSM) cells. Here, we used the whole cell patch-clamp technique to further characterize biophysical pro...

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Vydáno v:Am J Physiol Cell Physiol
Hlavní autoři: Yarotskyy, Viktor, Malysz, John, Petkov, Georgi V.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962517/
https://ncbi.nlm.nih.gov/pubmed/31577513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00189.2019
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