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Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia

Asparagine Synthetase (ASNS) catalyzes the synthesis of the non-essential amino acid asparagine (Asn) from aspartate (Asp) and glutamine (Gln). ASNS expression is highly regulated at the transcriptional level, being induced by both the Amino Acid Response (AAR) and the Unfolded Protein Response (UPR...

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Bibliografski detalji
Izdano u:Front Oncol
Glavni autori: Chiu, Martina, Taurino, Giuseppe, Bianchi, Massimiliano G., Kilberg, Michael S., Bussolati, Ovidio
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962308/
https://ncbi.nlm.nih.gov/pubmed/31998641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01480
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