Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia

Asparagine Synthetase (ASNS) catalyzes the synthesis of the non-essential amino acid asparagine (Asn) from aspartate (Asp) and glutamine (Gln). ASNS expression is highly regulated at the transcriptional level, being induced by both the Amino Acid Response (AAR) and the Unfolded Protein Response (UPR...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Chiu, Martina, Taurino, Giuseppe, Bianchi, Massimiliano G., Kilberg, Michael S., Bussolati, Ovidio
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Oncology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962308/
https://ncbi.nlm.nih.gov/pubmed/31998641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01480
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