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Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia

Asparagine Synthetase (ASNS) catalyzes the synthesis of the non-essential amino acid asparagine (Asn) from aspartate (Asp) and glutamine (Gln). ASNS expression is highly regulated at the transcriptional level, being induced by both the Amino Acid Response (AAR) and the Unfolded Protein Response (UPR...

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Dades bibliogràfiques
Publicat a:Front Oncol
Autors principals: Chiu, Martina, Taurino, Giuseppe, Bianchi, Massimiliano G., Kilberg, Michael S., Bussolati, Ovidio
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962308/
https://ncbi.nlm.nih.gov/pubmed/31998641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01480
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