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Asparagine synthetase: Function, structure, and role in disease

Asparagine synthetase (ASNS) converts aspartate and glutamine to asparagine and glutamate in an ATP-dependent reaction. ASNS is present in most, if not all, mammalian organs, but varies widely in basal expression. Human ASNS activity is highly responsive to cellular stress, primarily by increased tr...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Lomelino, Carrie L., Andring, Jacob T., McKenna, Robert, Kilberg, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723983/
https://ncbi.nlm.nih.gov/pubmed/29084849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.819060
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