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Asparagine synthetase: Function, structure, and role in disease

Asparagine synthetase (ASNS) converts aspartate and glutamine to asparagine and glutamate in an ATP-dependent reaction. ASNS is present in most, if not all, mammalian organs, but varies widely in basal expression. Human ASNS activity is highly responsive to cellular stress, primarily by increased tr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lomelino, Carrie L., Andring, Jacob T., McKenna, Robert, Kilberg, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723983/
https://ncbi.nlm.nih.gov/pubmed/29084849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.819060
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