Uncoupled turnover disrupts mitochondrial quality control in diabetic retinopathy

Mitochondrial quality control (MQC) is crucial for regulating CNS homeostasis, and its disruption has been implicated in the pathogenesis of some of the most common neurodegenerative diseases. In healthy tissues, the maintenance of MQC depends upon an exquisite balance between mitophagy (removal of...

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Foilsithe in:JCI Insight
Main Authors: Hombrebueno, Jose R., Cairns, Lauren, Dutton, Louise R., Lyons, Timothy J., Brazil, Derek P., Moynagh, Paul, Curtis, Tim M., Xu, Heping
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2019
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962019/
https://ncbi.nlm.nih.gov/pubmed/31661466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129760
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