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Uncoupled turnover disrupts mitochondrial quality control in diabetic retinopathy
Mitochondrial quality control (MQC) is crucial for regulating CNS homeostasis, and its disruption has been implicated in the pathogenesis of some of the most common neurodegenerative diseases. In healthy tissues, the maintenance of MQC depends upon an exquisite balance between mitophagy (removal of...
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| Publié dans: | JCI Insight |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6962019/ https://ncbi.nlm.nih.gov/pubmed/31661466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129760 |
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