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Nitric Oxide Inhibits Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia by Increasing the Ubiquitination and Degradation of UbcH10

Nitric oxide (NO) limits formation of neointimal hyperplasia in animal models of arterial injury in large part by inhibiting vascular smooth muscle cell (VSMC) proliferation through cell cycle arrest. The ubiquitin-conjugating enzyme UbcH10 is responsible for ubiquitinating cell cycle proteins for p...

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Publicado en:Cell Biochem Biophys
Main Authors: Tsihlis, Nick D., Oustwani, Chris S., Vavra, Ashley K., Jiang, Qun, Keefer, Larry K., Kibbe, Melina R.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959532/
https://ncbi.nlm.nih.gov/pubmed/21448667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-011-9179-3
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