Nitric oxide may inhibit neointimal hyperplasia by decreasing isopeptidase T levels and activity in the vasculature

OBJECTIVE: Isopeptidase T is a cysteine protease deubiquitinating enzyme that hydrolyzes unanchored polyubiquitin chains to free monoubiquitin. Nitric oxide (NO) decreases 26S proteasome activity in vascular smooth muscle cells (VSMCs) and inhibits neointimal hyperplasia in animal models. As NO can...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Tsihlis, Nick D., Kapadia, Muneera R., Vavra, Ashley K., Flannery, Walker D., Oustwani, Christopher S., Jiang, Qun, Kibbe, Melina R.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696405/
https://ncbi.nlm.nih.gov/pubmed/23375434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2012.10.066
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker