Nitric Oxide Increases Lysine 48-Linked Ubiquitination Following Arterial Injury

INTRODUCTION: Proteins are targeted for degradation by the addition of a polyubiquitin chain. Chains of ubiquitin linked via lysine 48 (K48) are associated with protein degradation while chains linked via lysine 63 (K63) are associated with intracellular signaling. We have previously shown that nitr...

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Main Authors: Oustwani, Chris S., Tsihlis, Nick D., Vavra, Ashley K., Jiang, Qun, Martinez, Janet, Kibbe, Melina R.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154506/
https://ncbi.nlm.nih.gov/pubmed/21737094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2011.05.032
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