Granulysin Delivered by Cytotoxic Cells Damages Endoplasmic Reticulum and Activates Caspase-7 in Target Cells

Granulysin is a human cytolytic molecule present in cytotoxic granules with perforin and granzymes. Recombinant 9-kDa granulysin kills a variety of microbes, including bacteria, yeast, fungi, and parasites, and induces apoptosis in tumor cells by causing intracellular calcium overload, mitochondrial...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Saini, Reena V., Wilson, Christine, Finn, Michael W., Wang, Tianhong, Krensky, Alan M., Clayberger, Carol
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959523/
https://ncbi.nlm.nih.gov/pubmed/21296981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003409
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker