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Expression and purification of 15 kDa granulysin utilizing an insect cell secretion system

Granulysin is an antimicrobial and proinflammatory protein expressed in activated human T cells and natural killer cells. A single mRNA produces the 15 kDa isoform which is then cleaved at the amino and carboxy termini to produce the 9 kDa isoform. Recombinant 9 kDa granulysin has been studied in de...

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Detalhes bibliográficos
Main Authors: Finn, Michael W., Clayberger, Carol, Krensky, Alan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966544/
https://ncbi.nlm.nih.gov/pubmed/20674748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2010.07.009
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