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Hemolysis of Erythrocytes by Granulysin-Derived Peptides but Not by Granulysin

Granulysin, a 9-kDa protein localized in human cytolytic T lymphoctyes and natural killer cell granules, is cytolytic against tumors and microbes but not against red blood cells. Synthetic peptides corresponding to the central region of granulysin recapitulate the lytic activity of the intact molecu...

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Publicado no:Antimicrob Agents Chemother
Principais autores: Li, Qing, Dong, Chen, Deng, Anmei, Katsumata, Masao, Nakadai, Ari, Kawada, Tomoyuki, Okada, Satoshi, Clayberger, Carol, Krensky, Alan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2005
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538851/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616319/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.1.388-397.2005
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