Hemolysis of Erythrocytes by Granulysin-Derived Peptides but Not by Granulysin

Granulysin, a 9-kDa protein localized in human cytolytic T lymphoctyes and natural killer cell granules, is cytolytic against tumors and microbes but not against red blood cells. Synthetic peptides corresponding to the central region of granulysin recapitulate the lytic activity of the intact molecu...

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Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Li, Qing, Dong, Chen, Deng, Anmei, Katsumata, Masao, Nakadai, Ari, Kawada, Tomoyuki, Okada, Satoshi, Clayberger, Carol, Krensky, Alan M.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2005
Témata:	Mechanisms of Action: Physiological Effects
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538851/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616319/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.1.388-397.2005
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