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Hemolysis of Erythrocytes by Granulysin-Derived Peptides but Not by Granulysin

Granulysin, a 9-kDa protein localized in human cytolytic T lymphoctyes and natural killer cell granules, is cytolytic against tumors and microbes but not against red blood cells. Synthetic peptides corresponding to the central region of granulysin recapitulate the lytic activity of the intact molecu...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Li, Qing, Dong, Chen, Deng, Anmei, Katsumata, Masao, Nakadai, Ari, Kawada, Tomoyuki, Okada, Satoshi, Clayberger, Carol, Krensky, Alan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2005
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538851/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616319/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.1.388-397.2005
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