Hemolysis of Erythrocytes by Granulysin-Derived Peptides but Not by Granulysin

Granulysin, a 9-kDa protein localized in human cytolytic T lymphoctyes and natural killer cell granules, is cytolytic against tumors and microbes but not against red blood cells. Synthetic peptides corresponding to the central region of granulysin recapitulate the lytic activity of the intact molecu...

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Autores principales: Li, Qing, Dong, Chen, Deng, Anmei, Katsumata, Masao, Nakadai, Ari, Kawada, Tomoyuki, Okada, Satoshi, Clayberger, Carol, Krensky, Alan M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC538851/
https://ncbi.nlm.nih.gov/pubmed/15616319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.388-397.2005
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