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Inhibition of PIM2 in liver cancer decreases tumor cell proliferation in vitro and in vivo primarily through the modulation of cell cycle progression

Liver cancer is the fourth leading cause of cancer-related mortality worldwide with limited therapeutic options. Thus, novel treatment strategies are urgently required. While the oncogenic kinase, proviral integration site for Moloney murine leukemia virus 2 (PIM2), has been shown to be overexpresse...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: Kronschnabl, Pia, Grünweller, Arnold, Hartmann, Roland K., Aigner, Achim, Weirauch, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959465/
https://ncbi.nlm.nih.gov/pubmed/31894300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4936
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