Functional Role and Therapeutic Potential of the Pim-1 Kinase in Colon Carcinoma

PURPOSE: The provirus integration site for Moloney murine leukemia virus 1 (Pim-1) kinase is overexpressed in various tumors and has been linked to poor prognosis. Its role as proto-oncogene is based on several Pim-1 target proteins involved in pivotal cellular processes. Here, we explore the functi...

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Bibliographic Details
Main Authors: Weirauch, Ulrike, Beckmann, Nadine, Thomas, Maren, Grünweller, Arnold, Huber, Kilian, Bracher, Franz, Hartmann, Roland K, Aigner, Achim
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689241/
https://ncbi.nlm.nih.gov/pubmed/23814490
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