PEI-complexed LNA antiseeds as miRNA inhibitors

Antisense inhibition of oncogenic or other disease-related miRNAs and miRNA families in vivo may provide novel therapeutic strategies. However, this approach relies on the development of potent miRNA inhibitors and their efficient delivery into cells. Here, we introduce short seed-directed LNA oligo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Thomas, Maren, Lange-Grünweller, Kerstin, Dayyoub, Eyas, Bakowsky, Udo, Weirauch, Ulrike, Aigner, Achim, Hartmann, Roland K., Grünweller, Arnold
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2012
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551863/
https://ncbi.nlm.nih.gov/pubmed/22894918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.21165
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