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U1 Adaptors for the Therapeutic Knockdown of the Oncogene Pim-1 Kinase in Glioblastoma

U1 small nuclear interference (U1i) has recently been described as a novel gene silencing mechanism. U1i employs short oligonucleotides, so-called U1 adaptors, for specific gene knockdown, expanding the field of current silencing strategies that are primarily based on RNA interference (RNAi) or anti...

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Detalhes bibliográficos
Main Authors: Weirauch, Ulrike, Grünweller, Arnold, Cuellar, Luis, Hartmann, Roland K., Aigner, Achim
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723237/
https://ncbi.nlm.nih.gov/pubmed/23724780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0407
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