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Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis

Differentiation and homeostasis of Foxp3(+) regulatory T (Treg) cells are strictly controlled by T-cell receptor (TCR) signals; however, molecular mechanisms that govern these processes are incompletely understood. Here we show that Bach2 is an important regulator of Treg cell differentiation and ho...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Sidwell, Tom, Liao, Yang, Garnham, Alexandra L., Vasanthakumar, Ajithkumar, Gloury, Renee, Blume, Jonas, Teh, Peggy P., Chisanga, David, Thelemann, Christoph, de Labastida Rivera, Fabian, Engwerda, Christian R., Corcoran, Lynn, Kometani, Kohei, Kurosaki, Tomohiro, Smyth, Gordon K., Shi, Wei, Kallies, Axel
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959360/
https://ncbi.nlm.nih.gov/pubmed/31937752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14112-2
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