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Bach2 maintains T cells in a naive state by suppressing effector memory-related genes

The transcriptional repressor BTB and CNC homology 2 (Bach2) is thought to be mainly expressed in B cells with specific functions such as class switch recombination and somatic hypermutation, but its function in T cells is not known. We found equal Bach2 expression in T cells and analyzed its functi...

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Detalhes bibliográficos
Main Authors: Tsukumo, Shin-ichi, Unno, Midori, Muto, Akihiko, Takeuchi, Arata, Kometani, Kohei, Kurosaki, Tomohiro, Igarashi, Kazuhiko, Saito, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696756/
https://ncbi.nlm.nih.gov/pubmed/23754397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306691110
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