JNK/AP1 Pathway Regulates MYC Expression and BCR Signaling through Ig Enhancers in Burkitt Lymphoma Cells

In Burkitt lymphoma (BL), a chromosomal translocation by which the MYC gene is fused to an immunoglobulin (Ig) gene locus is frequently found. The translocated MYC gene is overexpressed, which is the major driver of BL tumorigenesis. Studies have shown that Ig enhancers are essential for MYC overexp...

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Bibliografiske detaljer
Udgivet i:J Cancer
Main Authors: Ding, Xiaoling, Wang, Xiaoying, Zhu, Xueting, Zhang, Jie, Zhu, Yiqing, Shao, Xiaoyi, Zhou, Xiaorong
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959055/
https://ncbi.nlm.nih.gov/pubmed/31942184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.34055
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