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YY1 binds to the E3ʹ enhancer and inhibits the expression of the immunoglobulin κ gene via epigenetic modifications

The rearrangement and expression of immunoglobulin genes are regulated by enhancers and their binding transcriptional factors that activate or suppress the activities of the enhancers. The immunoglobulin κ (Igκ) gene locus has three important enhancers: the intrinsic enhancer (Ei), 3′ enhancer (E3′)...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Zhou, Xiaorong, Xian, Weiwei, Zhang, Jie, Zhu, Yiqing, Shao, Xiaoyi, Han, Yu, Qi, Yue, Ding, Xiaoling, Wang, Xiaoying
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231012/
https://ncbi.nlm.nih.gov/pubmed/30098214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12990
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