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YY1 binds to the E3ʹ enhancer and inhibits the expression of the immunoglobulin κ gene via epigenetic modifications

The rearrangement and expression of immunoglobulin genes are regulated by enhancers and their binding transcriptional factors that activate or suppress the activities of the enhancers. The immunoglobulin κ (Igκ) gene locus has three important enhancers: the intrinsic enhancer (Ei), 3′ enhancer (E3′)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Immunology
Hauptverfasser: Zhou, Xiaorong, Xian, Weiwei, Zhang, Jie, Zhu, Yiqing, Shao, Xiaoyi, Han, Yu, Qi, Yue, Ding, Xiaoling, Wang, Xiaoying
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231012/
https://ncbi.nlm.nih.gov/pubmed/30098214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12990
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