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Burkitt lymphoma beyond MYC translocation: N-MYC and DNA methyltransferases dysregulation
BACKGROUND: The oncogenic transcription factor MYC is pathologically activated in many human malignancies. A paradigm for MYC dysregulation is offered by Burkitt lymphoma, where chromosomal translocations leading to Immunoglobulin gene-MYC fusion are the crucial initiating oncogenic events. However,...
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Foilsithe in: | BMC Cancer |
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Main Authors: | , , , , , , , , , , , , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
BioMed Central
2015
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4600215/ https://ncbi.nlm.nih.gov/pubmed/26453442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1661-7 |
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