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Distinct roles of XRCC1 in genome integrity in Xenopus egg extracts

Oxidative DNA damage represents one of the most abundant DNA lesions. It remains unclear how DNA repair and DNA damage response (DDR) pathways are coordinated and regulated following oxidative stress. While XRCC1 has been implicated in DNA repair, it remains unknown how exactly oxidative DNA damage...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Cupello, Steven, Lin, Yunfeng, Yan, Shan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959006/
https://ncbi.nlm.nih.gov/pubmed/31808793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190798
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