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REV1 is important for the ATR-Chk1 DNA damage response pathway in Xenopus egg extracts

The translesion DNA synthesis (TLS) polymerase REV1 is implicated in the bypass of the irreparable DNA damage such as interstrand crosslinks (ICLs). However, the potential role of REV1 in DNA damage response (DDR) pathway has not been determined. In this research communication, we provide evidence t...

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Pubblicato in:Biochem Biophys Res Commun
Autori principali: DeStephanis, Darla, McLeod, Melissa, Yan, Shan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426025/
https://ncbi.nlm.nih.gov/pubmed/25800873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.03.077
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