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Methods for studying DNA single-strand break repair and signaling in Xenopus laevis egg extracts

DNA single-strand breaks (SSBs) are the most common type of DNA lesions as they are generated approximately 10,000 times per mammalian cell each day. Unrepaired SSBs compromise DNA replication and transcription programs, leading to genome instability, and have been implicated in many diseases includ...

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Détails bibliographiques
Publié dans:Methods Mol Biol
Auteurs principaux: Lin, Yunfeng, Ha, Anh, Yan, Shan
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550457/
https://ncbi.nlm.nih.gov/pubmed/31127575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9500-4_9
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