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Methods for studying DNA single-strand break repair and signaling in Xenopus laevis egg extracts

DNA single-strand breaks (SSBs) are the most common type of DNA lesions as they are generated approximately 10,000 times per mammalian cell each day. Unrepaired SSBs compromise DNA replication and transcription programs, leading to genome instability, and have been implicated in many diseases includ...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Lin, Yunfeng, Ha, Anh, Yan, Shan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550457/
https://ncbi.nlm.nih.gov/pubmed/31127575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9500-4_9
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